Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors

In the present study, we have evaluated a boronated dendrimer-epidermal growth factor (BD-EGF) bioconjugate as a molecular targeting agent for boron neutron capture therapy (BNCT) of the human EGFR gene-transfected F98 rat glioma, designated F98(EGFR). EGF was chemically linked to a heavily boronate...

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Detalhes bibliográficos
Main Authors: Yang, Weilian, Barth, Rolf F., Wu, Gong, Huo, Tianyao, Tjarks, Werner, Ciesielski, Michael, Fenstermaker, Robert A., Ross, Brain D., Wikstrand, Carol J., Riley, Kent J., Binns, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830857/
https://ncbi.nlm.nih.gov/pubmed/19588228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9945-x
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