Cycling of Gut Mucosal CD4+ T Cells Decreases after Prolonged Anti-Retroviral Therapy and is Associated with Plasma LPS Levels

The gut mucosa is an important site of HIV immunopathogenesis, with severe depletion of CD4+ T cells occurring during acute infection. The effect of prolonged anti-retroviral therapy (ART) on cycling and restoration of T lymphocytes in the gut remains unclear. Colon and terminal ileal biopsies and p...

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Bibliographische Detailangaben
Hauptverfasser: Ciccone, Emily J., Read, Sarah W., Mannon, Peter J., Yao, Michael D., Hodge, Jessica N., Dewar, Robin, Chairez, Cheryl L., Proschan, Michael A., Kovacs, Joseph A., Sereti, Irini
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830855/
https://ncbi.nlm.nih.gov/pubmed/19956090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.129
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