CD4(+) T Cells, Including Th17 and Cycling Subsets, Are Intact in the Gut Mucosa of HIV-1-Infected Long-Term Nonprogressors

During acute human immunodeficiency virus (HIV) infection, there is a massive depletion of CD4(+) T cells in the gut mucosa that can be reversed to various degrees with antiretroviral therapy. Th17 cells have been implicated in mucosal immunity to extracellular bacteria, and preservation of this sub...

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Bibliographische Detailangaben
Hauptverfasser: Ciccone, Emily J., Greenwald, Jamieson H., Lee, Philip I., Biancotto, Angélique, Read, Sarah W., Yao, Michael A., Hodge, Jessica N., Thompson, William L., Kovacs, Stephen B., Chairez, Cheryl L., Migueles, Stephen A., Kovacs, Joseph A., Margolis, Leonid B., Sereti, Irini
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126290/
https://ncbi.nlm.nih.gov/pubmed/21471231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02643-10
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