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Roles of retrotransposons in benign and malignant hematologic disease

Nearly half of our genomes are repetitive sequences derived from retrotransposons. These repeats have accumulated by a ‘copy-and-paste’ mechanism whereby: (i.) a genomic template sequence is transcribed to RNA, (ii.) the RNA is reverse-transcribed, and (iii.) the DNA copy is inserted at a new locati...

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Dettagli Bibliografici
Autori principali: Schneider, Anna M., Duffield, Amy S., Symer, David E., Burns, Kathleen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830787/
https://ncbi.nlm.nih.gov/pubmed/20200603
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