Azide and Tween-20 reduce binding to autoantibody epitopes of islet antigen-2; implications for assay performance and reproducibility

Autoantibodies to islet antigen 2 (IA-2A) are important markers for predicting diabetes in children and young adults. Harmonization of IA-2A assay measurement is essential if results from different laboratories are to be compared. We investigated whether sodium azide, a bacteriostatic agent added to...

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Main Authors: Williams, Alistair JK, Somerville, Michelle, Rokni, Saba, Bonifacio, Ezio, Yu, Liping, Eisenbarth, George, Akolkar, Beena, Steffes, Michael, Bingley, Polly J
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830747/
https://ncbi.nlm.nih.gov/pubmed/19837075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.10.004
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