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A Source for the Special Catalytic Power of Enzymes: Orbital Steering

The velocities of acid catalyzed esterification and γ-lactonizations were studied to test the sensitivity of a chemical reaction to the orientation of the reacting atoms. Variation in orientation of the attacking oxygen atom relative to the carbon atom of the carboxylic acid was achieved by using bi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Storm, Dan R., Koshland, D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283065/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16591843/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.2.445
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