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Reconsidering the asymptotic null distribution of likelihood ratio tests for genetic linkage in multivariate variance components models under complete pleiotropy

Accurate knowledge of the null distribution of hypothesis tests is important for valid application of the tests. In previous papers and software, the asymptotic null distribution of likelihood ratio tests for detecting genetic linkage in multivariate variance components models has been stated to be...

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Detalles Bibliográficos
Main Authors: Han, Summer S., Chang, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830577/
https://ncbi.nlm.nih.gov/pubmed/20029057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxp054
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