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Reconsidering the asymptotic null distribution of likelihood ratio tests for genetic linkage in multivariate variance components models under complete pleiotropy

Accurate knowledge of the null distribution of hypothesis tests is important for valid application of the tests. In previous papers and software, the asymptotic null distribution of likelihood ratio tests for detecting genetic linkage in multivariate variance components models has been stated to be...

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Détails bibliographiques
Auteurs principaux: Han, Summer S., Chang, Joseph T.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830577/
https://ncbi.nlm.nih.gov/pubmed/20029057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxp054
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