WWP-1 Is a Novel Modulator of the DAF-2 Insulin-Like Signaling Network Involved in Pore-Forming Toxin Cellular Defenses in Caenorhabditis elegans

Pore-forming toxins (PFTs) are the single largest class of bacterial virulence factors. The DAF-2 insulin/insulin-like growth factor-1 signaling pathway, which regulates lifespan and stress resistance in Caenorhabditis elegans, is known to mutate to resistance to pathogenic bacteria. However, its ro...

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Main Authors: Chen, Chang-Shi, Bellier, Audrey, Kao, Cheng-Yuan, Yang, Ya-Luen, Chen, Huan-Da, Los, Ferdinand C. O., Aroian, Raffi V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830483/
https://ncbi.nlm.nih.gov/pubmed/20209166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009494
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