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Microscopic Basis for the Mesoscopic Extensibility of Dendrimer-Compacted DNA
The mechanism of DNA compaction by dendrimers is key to the design of nanotechnologies that can deliver genetic material into cells. We present atomistic simulations, mesoscopic modeling and single-molecule pulling experiments describing DNA dendrimer interactions. All-atom molecular dynamics were u...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830442/ https://ncbi.nlm.nih.gov/pubmed/20197037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.020 |
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