SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol

Endothelial nitric oxide synthase (eNOS) plays a crucial role in endothelial cell functions. SIRT1, a NAD(+)-dependent deacetylase, is shown to regulate endothelial function and hence any alteration in endothelial SIRT1 will affect normal vascular physiology. Cigarette smoke (CS)-mediated oxidative...

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Autores principales: Arunachalam, Gnanapragasam, Yao, Hongwei, Sundar, Isaac K, Caito, Samuel, Rahman, Irfan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830376/
https://ncbi.nlm.nih.gov/pubmed/20102704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.01.080
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