APOE Predicts Aβ but not Tau Alzheimer’s Pathology in Cognitively Normal Aging

OBJECTIVE: To examine interactions of Apolipoprotein E (APOE) genotype with age and with in vivo measures of preclinical Alzheimer’s disease (AD) in cognitively normal aging. METHODS: Two hundred and 41 cognitively normal individuals, age 45 to 88 years, had cerebral amyloid imaging studies with Pit...

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Hauptverfasser: Morris, John C., Roe, Catherine M., Xiong, Chengjie, Fagan, Anne M, Goate, Alison M., Holtzman, David M., Mintun, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830375/
https://ncbi.nlm.nih.gov/pubmed/20186853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21843
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