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Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite

[Image: see text] A new and efficient route to the recently reported 3-nitro-2-ethyldibenzofuran caging group was developed. Furthermore, its installation on a thymidine phosphoramidite is described. This caging group is efficiently removed through light-irradiation at 365 nm.

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Autores principales: Lusic, Hrvoje, Uprety, Rajendra, Deiters, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830370/
https://ncbi.nlm.nih.gov/pubmed/20112966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902807q
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