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Frequency of Factor H-binding Protein Modular Groups and Susceptibility to Cross-reactive Bactericidal Activity in Invasive Meningococcal Isolates

Meningococcal factor H binding protein (fHbp) is a promising vaccine candidate that elicits serum bactericidal antibodies in humans. Based on sequence variability of the entire protein, fHbp has been divided into three variant groups or two sub-families. We recently reported that the fHbp architectu...

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Main Authors: Pajon, Rolando, Beernink, Peter T., Harrison, Lee H., Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830318/
https://ncbi.nlm.nih.gov/pubmed/20044056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.12.027
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