High Density DNA Array Analysis Reveals Distinct Genomic Profiles in a Subset of Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) generally harbor activating mutations in KIT or PDGFRA. Mutations in these receptor tyrosine kinases lead to dysregulation of downstream signaling pathways that contribute to GIST pathogenesis. GISTs with KIT or PDGFRA mutations also undergo secondary cytogene...

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Bibliografiska uppgifter
Huvudupphovsmän: Belinsky, Martin G., Skorobogatko, Yuliya V., Rink, Lori, Pei, Jianming, Cai, Kathy Q., Vanderveer, Lisa A., Riddell, David, Merkel, Erin, Tarn, Chi, Eisenberg, Burton L., von Mehren, Margaret, Testa, Joseph R., Godwin, Andrew K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830286/
https://ncbi.nlm.nih.gov/pubmed/19585585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20689
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