NF-κB Activation in Airways Modulates Allergic Inflammation but Not Hyperresponsiveness

Airways display robust NF-κB activation and represent targets for anti-inflammatory asthma therapies, but the functional importance of NF-κB activation in airway epithelium remains enigmatic. Therefore, transgenic mice were created in which NF-κB activation is repressed specifically in airways (CC10...

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Hauptverfasser: Poynter, Matthew E., Cloots, Roy, van Woerkom, Tiest, Butnor, Kelly J., Vacek, Pamela, Taatjes, Douglas J., Irvin, Charles G., Janssen-Heininger, Yvonne M. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830271/
https://ncbi.nlm.nih.gov/pubmed/15557197
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