Pleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-γ/JAK/STAT1 signaling is critical for the expression of PTN in macrophages

Neovascularization is critical to destabilization of atheroma. We previously reported that the angiogenic growth factor pleiotrophin (PTN) coaxes monocytes to assume the phenotype of functional endothelial cells in vitro and in vivo. In this study we show that PTN expression is colocalized with capi...

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Autori principali: Li, Fuqiang, Tian, Fang, Wang, Lai, Williamson, Ian K., Sharifi, Behrooz G., Shah, Prediman K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Federation of American Societies for Experimental Biology 2010
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830133/
https://ncbi.nlm.nih.gov/pubmed/19917672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-140780
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