Activation-induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4(+) T cells

BTLA, a recently cloned coreceptor expressed on lymphocytes, negatively regulates cell activation by recruiting SHP-1/SHP-2. However, the mechanisms that regulate the intracellular localization of BTLA and its trafficking to the cell surface in T cells are still unknown. To determine the mechanisms...

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Autors principals: Owada, Takayoshi, Watanabe, Norihiko, Oki, Mie, Oya, Yoshihiro, Saito, Yasushi, Saito, Takashi, Iwamoto, Itsuo, Murphy, Theresa L., Murphy, Kenneth M., Nakajima, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: The Society for Leukocyte Biology 2010
Matèries:
Receptors, Signal Transduction, & Genes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830123/
https://ncbi.nlm.nih.gov/pubmed/19892849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0309138
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