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Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection

Alzheimer's disease (AD), the major contributor to dementia in the elderly, involves accumulation in the brain of extracellular plaques containing the β-amyloid protein (Aβ) and intracellular neurofibrillary tangles of hyperphosphorylated tau protein. AD is also characterized by a loss of neuro...

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Detalhes bibliográficos
Main Authors: Buckingham, Steven D., Jones, Andrew K., Brown, Laurence A., Sattelle, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830120/
https://ncbi.nlm.nih.gov/pubmed/19293145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.108.000562
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