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Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK

Highly purified oligodendroglial lineage cells from mice lacking functional bax and bak genes were resistant to apoptosis after in vitro differentiation, indicating an essential role of the intrinsic apoptotic pathway in apoptosis of oligodendrocytes in the absence of neurons (axons) and other glial...

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Библиографические подробности
Главные авторы: Kawai, Kumi, Itoh, Takayuki, Itoh, Aki, Horiuchi, Makoto, Wakayama, Kouji, Bannerman, Peter, Garbern, James Y., Pleasure, David, Lindsten, Tullia
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830116/
https://ncbi.nlm.nih.gov/pubmed/20128842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.06988.x
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