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Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK

Highly purified oligodendroglial lineage cells from mice lacking functional bax and bak genes were resistant to apoptosis after in vitro differentiation, indicating an essential role of the intrinsic apoptotic pathway in apoptosis of oligodendrocytes in the absence of neurons (axons) and other glial...

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Bibliografiske detaljer
Main Authors: Kawai, Kumi, Itoh, Takayuki, Itoh, Aki, Horiuchi, Makoto, Wakayama, Kouji, Bannerman, Peter, Garbern, James Y., Pleasure, David, Lindsten, Tullia
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830116/
https://ncbi.nlm.nih.gov/pubmed/20128842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.06988.x
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