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Progesterone Receptor Isoform Functions in Normal Breast Development and Breast Cancer

Progesterone acting through two isoforms of the progesterone receptor (PR), PRA and PRB, regulates proliferation and differentiation in the normal mammary gland in mouse, rat and human. Progesterone and PR have also been implicated in the etiology and pathogenesis of human breast cancer. The focus o...

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Bibliographic Details
Main Authors: Kariagina, Anastasia, Aupperlee, Mark D., Haslam, Sandra Z.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829978/
https://ncbi.nlm.nih.gov/pubmed/18197783
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