ACTH Receptors in the Adrenal: Specific Binding of ACTH-(125)I and Its Relation to Adenyl Cyclase

Pure monoiodo ACTH-(125)I was prepared that was biologically active and free of unlabeled ACTH. Extracts of adrenal cortex that contained ACTH-sensitive adenyl cyclase, bound ACTH-(125)I; extracts that lacked the ACTH-sensitive cyclase did not bind ACTH-(125)I. Unlabeled ACTH inhibited the binding o...

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Autores principales: Lefkowitz, Robert J., Roth, Jesse, Pricer, William, Pastan, Ira
Formato: Artigo
Lenguaje:Inglês
Publicado: 1970
Materias:
Biological Sciences: Biochemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC282969/
https://ncbi.nlm.nih.gov/pubmed/4315615
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