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ACTH Receptors in the Adrenal: Specific Binding of ACTH-(125)I and Its Relation to Adenyl Cyclase

Pure monoiodo ACTH-(125)I was prepared that was biologically active and free of unlabeled ACTH. Extracts of adrenal cortex that contained ACTH-sensitive adenyl cyclase, bound ACTH-(125)I; extracts that lacked the ACTH-sensitive cyclase did not bind ACTH-(125)I. Unlabeled ACTH inhibited the binding o...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lefkowitz, Robert J., Roth, Jesse, Pricer, William, Pastan, Ira
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1970
Fag:
Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4315615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.745
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