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Synthesis of Amido-Spiro[2.2]Pentanes via Simmons-Smith Cyclopropanation of Allenamides.

A detailed account on Simmons-Smith cyclopropanations of allenamides en route to amido-spiro[2.2]pentanes is described here. While the diastereoselectivity was low when using unsubstituted allenamides, the reaction is overall efficient and general, representing the most direct synthesis of both chem...

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Autors principals: Lu, Ting, Hayashi, Ryuji, Hsung, Richard P., DeKrover, Kyle A., Lohse, Andrew G., Song, Zhenlei, Tang, Yu
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829688/
https://ncbi.nlm.nih.gov/pubmed/19641792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b908205k
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