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Selection and Characterization of an E. coli Mutant Defective in Membrane Lipid Biosynthesis

A procedure is described for the selection of temperature-sensitive phospholipid mutants based upon radiation suicide of the wild-type organisms by tritiated L-glycerol-3-phosphate incorporated in the phospholipids. One of these mutants possesses an acyltransferase activity much more thermolabile th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cronan, John E., Ray, Tapas K., Vagelos, P. Roy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4910856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.737
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