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Loss of estrogen receptor β decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice

Platelets derived from aged (reproductively senescent) female mice with genetic deletion of estrogen receptor beta (βER) are more thrombogenic than those from age-matched wild-type (WT) mice. Intracellular processes contributing to this increased thrombogenicity are not known. Experiments were desig...

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Detalhes bibliográficos
Main Authors: Jayachandran, Muthuvel, Preston, Claudia C., Hunter, Larry W., Jahangir, Arshad, Owen, Whyte G., Korach, Kenneth S., Miller, Virginia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829645/
https://ncbi.nlm.nih.gov/pubmed/19908165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-009-9119-y
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