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Leukocyte- and Platelet-Derived Microvesicle Interactions following In Vitro and In Vivo Activation of Toll-Like Receptor 4 by Lipopolysaccharide

BACKGROUND: Pro-coagulant membrane microvesicles (MV) derived from platelets and leukocytes are shed into the circulation following receptor-mediated activation, cell-cell interaction, and apoptosis. Platelets are sentinel markers of toll-like receptor 4 (TLR4) activation. Experiments were designed...

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Detalhes bibliográficos
Main Authors: Xiong, Jing, Miller, Virginia M., Hunter, Larry W., Li, Yunman, Jayachandran, Muthuvel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180459/
https://ncbi.nlm.nih.gov/pubmed/21966536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025504
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