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Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation

BACKGROUND: Studies indicate that the 19S proteasome contributes to chromatin reorganization, independent of the role the proteasome plays in protein degradation. We have previously shown that components of the 19S proteasome are crucial for regulating inducible histone activation events in mammalia...

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Autors principals: Koues, Olivia I, Mehta, Ninad T, Truax, Agnieszka D, Dudley, R Kyle, Brooks, Jeanne K, Greer, Susanna F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829561/
https://ncbi.nlm.nih.gov/pubmed/20181089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-5
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