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Derepression of GDP-α-D-Mannose and UDP-Glucose Pyrophosphorylases by a Regulator Gene Mutation; Episomal Dominance in Partial Diploids

Mutants of Escherichia coli K12 at the capR locus are overproduce capsular polysaccharide, and are derepressed for synthesis of several enzymes involved in capsular polysaccharide synthesis(1-3) including GDP-mannose pyrophosphorylase.(8) UDP-glucose pyrophosphorylase is also derepressed in a haploi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lieberman, Michael M., Buchanan, Christine E., Markovitz, Alvin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1970
Fag:
Biological Sciences: Genetics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4910851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.625
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