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Derepression of GDP-α-D-Mannose and UDP-Glucose Pyrophosphorylases by a Regulator Gene Mutation; Episomal Dominance in Partial Diploids

Mutants of Escherichia coli K12 at the capR locus are overproduce capsular polysaccharide, and are derepressed for synthesis of several enzymes involved in capsular polysaccharide synthesis(1-3) including GDP-mannose pyrophosphorylase.(8) UDP-glucose pyrophosphorylase is also derepressed in a haploi...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Lieberman, Michael M., Buchanan, Christine E., Markovitz, Alvin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1970
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4910851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.625
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