An excess of rare genetic variation in ABCE1 among Yorubans and African-American individuals with HIV-1

Signatures of natural selection occur throughout the human genome and can be detected at the sequence level. We have re-sequenced ABCE1, a host candidate gene essential for HIV-1 capsid assembly, in European- (n=23) and African-descent (Yoruban; n=24) reference populations for genetic variation disc...

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Detalhes bibliográficos
Main Authors: Crawford, Dana C., Zheng, Natalie, Speelmon, Emily C, Stanaway, Ian, Rieder, Mark J., Nickerson, Deborah A., McElrath, M. Juliana, Lingappa, Jairam
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829431/
https://ncbi.nlm.nih.gov/pubmed/19657357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.57
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