Hyperpolarized (13)C Spectroscopy and an NMR-Compatible Bioreactor System for the Investigation of Real-Time Cellular Metabolism

The purpose of this study was to combine a three-dimensional NMR-compatible bioreactor with hyperpolarized (13)C NMR spectroscopy in order to probe cellular metabolism in real time. JM1 (immortalized rat hepatoma) cells were cultured in a three-dimensional NMR-compatible fluidized bioreactor. (31)P...

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Hauptverfasser: Keshari, Kayvan R., Kurhanewicz, John, Jeffries, Rex E., Wilson, David M., Dewar, Brian J., Van Criekinge, Mark, Zierhut, Matthew, Vigneron, Daniel B., Macdonald, Jeffrey M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829258/
https://ncbi.nlm.nih.gov/pubmed/20099325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22225
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