In vitro and in vivo antineoplastic activity of a novel bromopyrrole and its potential mechanism of action

BACKGROUND AND PURPOSE: Many bromopyrrole compounds have been reported to have in vitro antineoplastic activity. In a previous study, we isolated N-(4, 5-dibromo-pyrrole-2-carbonyl)-L-amino isovaleric acid methyl ester (B6) from marine sponges. Here, we investigated the in vitro and in vivo antineop...

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Detalhes bibliográficos
Main Authors: Xiong, Sheng, Pang, Hui-dan, Fan, Jun, Ge, Feng, Yang, Xiao-xia, Liu, Qiu-ying, Liao, Xiao-jian, Xu, Shi-hai
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829216/
https://ncbi.nlm.nih.gov/pubmed/20067467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00573.x
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