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Inhibitory actions of diphenyleneiodonium on endothelium-dependent vasodilatations in vitro and in vivo.

1. This study examined the in vitro and in vivo inhibitory effects of diphenyleneiodonium (DPI), a novel inhibitor of nitric oxide (NO) synthase, on endothelium-dependent vasodilatations. 2. DPI (3 x 10(-8)-3 x 10(-6) M) concentration-dependently inhibited acetylcholine (ACh)-induced relaxation in p...

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Main Authors: Wang, Y. X., Poon, C. I., Poon, K. S., Pang, C. C.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175784/
https://ncbi.nlm.nih.gov/pubmed/7507779
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