Mutation discovery in the mouse using genetically guided array capture and re-sequencing

Forward genetics (phenotype driven approaches) remain the primary source for allelic variants in the mouse. Unfortunately, the gap between observable phenotype and causative genotype limits the widespread use of spontaneous and induced mouse mutants. As alternatives to traditional positional cloning...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: D'Ascenzo, Mark, Meacham, Carl, Kitzman, Jacob, Middle, Christina, Knight, Jim, Winer, Roger, Kukricar, Miroslav, Richmond, Todd, Albert, Thomas J., Czechanski, Anne, Donahue, Leah Rae, Affourtit, Jason, Jeddeloh, Jeffrey A., Reinholdt, Laura
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829192/
https://ncbi.nlm.nih.gov/pubmed/19629596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9200-y
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