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Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport

Cytoplasmic protein transport in axons (‘slow axonal transport') is essential for neuronal homeostasis, and involves Kinesin-1, the same motor for membranous organelle transport (‘fast axonal transport'). However, both molecular mechanisms of slow axonal transport and difference in usage o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Terada, Sumio, Kinjo, Masataka, Aihara, Makoto, Takei, Yosuke, Hirokawa, Nobutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829163/
https://ncbi.nlm.nih.gov/pubmed/20111006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.389
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