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Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head

Post-Golgi carriers of various newly synthesized axonal membrane proteins, which possess kinesin (KIF5)-driven highly processive motility, were transported from the TGN directly to axons. We found that KIF5 has a preference to the microtubules in the initial segment of axon. Low dose paclitaxel trea...

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Detalhes bibliográficos
Main Authors: Nakata, Takao, Hirokawa, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172855/
https://ncbi.nlm.nih.gov/pubmed/12975348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302175
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