Llwytho...

Her2 Activates NF-κB and Induces Invasion Through the Canonical Pathway Involving IKKα

The membrane bound receptor tyrosine kinase Her2 is overexpressed in approximately 30% of human breast cancers which correlates with poor prognosis. Her2-induced signaling pathways include MAPK and PI3K/Akt, of which the latter has been shown to be critical for Her2(+) breast cancer cell growth and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Merkhofer, Evan C, Cogswell, Patricia, Baldwin, Albert S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829103/
https://ncbi.nlm.nih.gov/pubmed/19946332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.410
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