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RASSF2 associates with and stabilises the proapoptotic kinase MST2

RASSF2 is a tumour suppressor that in common with the rest of the RASSF family contains Ras association and SARAH domains. We identified the proapoptotic kinases MST1 and MST2 as the most significant binding partners of RASSF2, confirmed the interactions at endogenous levels and demonstrated that RA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cooper, Wendy N, Hesson, Luke B, Matallanas, David, Dallol, Ashraf, von Kriegsheim, Alex, Ward, Robyn, Kolch, Walter, Latif, Farida
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829092/
https://ncbi.nlm.nih.gov/pubmed/19525978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.152
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