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Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes; here we describe a second major role for Brn3a in the specification of sensory subtypes...

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Autori principali: Dykes, Iain M, Lanier, Jason, Raisa Eng, S, Turner, Eric E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829025/
https://ncbi.nlm.nih.gov/pubmed/20096094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-5-3
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