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Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation

The transcription factor Brn3a, product of the pou4f1 gene, is expressed in most sensory neurons throughout embryogenesis. Prior work has demonstrated a role for Brn3a in the repression of early neurogenic genes; here we describe a second major role for Brn3a in the specification of sensory subtypes...

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Bibliografiske detaljer
Main Authors: Dykes, Iain M, Lanier, Jason, Raisa Eng, S, Turner, Eric E
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829025/
https://ncbi.nlm.nih.gov/pubmed/20096094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-5-3
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