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Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action

Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. One feature of VEGF is the existence of multiple isoforms arising from alternative exon splicing. Our initial biochemical and biological studies indicated that such isoforms are uni...

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Detalhes bibliográficos
Autor principal: Ferrara, Napoleone
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828956/
https://ncbi.nlm.nih.gov/pubmed/20185770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0590
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