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Defective B cell response to T-dependent immunization in lupus-prone mice

Lupus anti-nuclear Abs show the characteristics of Ag-driven T cell-dependent (TD) humoral responses. If autoAgs elicit the same response as exogenous Ags, lupus should enhance humoral responses to immunization. Blunted responses to various immunizations have, however, been reported in a significant...

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Detalhes bibliográficos
Main Authors: Niu, Haitao, Sobel, Eric S., Morel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828936/
https://ncbi.nlm.nih.gov/pubmed/18924209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838417
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