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Directly probing the mechanical properties of the spindle and its matrix

Several recent models for spindle length regulation propose an elastic pole to pole spindle matrix that is sufficiently strong to bear or antagonize forces generated by microtubules and microtubule motors. We tested this hypothesis using microneedles to skewer metaphase spindles in Xenopus laevis eg...

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Bibliographic Details
Main Authors: Gatlin, Jesse C., Matov, Alexandre, Danuser, Gaudenz, Mitchison, Timothy J., Salmon, Edward D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828919/
https://ncbi.nlm.nih.gov/pubmed/20176922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907110
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