Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth

Small cell lung cancer (SCLC) is an aggressive tumor, associated with ectopic ACTH syndrome. We have shown that SCLC cells are glucocorticoid receptor (GR) deficient, and that restoration of GR expression confers glucocorticoid sensitivity and induces apoptosis in vitro. To determine the effects of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sommer, Paula, Cowen, Rachel L, Berry, Andrew, Cookson, Ann, Telfer, Brian A, Williams, Kaye J, Stratford, Ian J, Kay, Paul, White, Anne, Ray, David W
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Endocrinology 2010
Assuntos:
Regular papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828806/
https://ncbi.nlm.nih.gov/pubmed/20015838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-09-0241
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados