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The Spontaneous Appearance Rate of the Yeast Prion [PSI+] and Its Implications for the Evolution of the Evolvability Properties of the [PSI+] System

Epigenetically inherited aggregates of the yeast prion [PSI+] cause genomewide readthrough translation that sometimes increases evolvability in certain harsh environments. The effects of natural selection on modifiers of [PSI+] appearance have been the subject of much debate. It seems likely that [P...

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Detalhes bibliográficos
Main Authors: Lancaster, Alex K., Bardill, J. Patrick, True, Heather L., Masel, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828720/
https://ncbi.nlm.nih.gov/pubmed/19917766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.110213
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