Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes

OBJECTIVE: The impact of the diabetes risk gene transcription factor 7-like 2 (TCF7L2) on body weight is unclear. As TCF7L2 is expressed in adipose tissue and involved in Wnt-dependent regulation of adipogenesis, we studied the impact of TCF7L2 variants on body composition and weight loss during lif...

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Auteurs principaux: Haupt, Axel, Thamer, Claus, Heni, Martin, Ketterer, Caroline, Machann, Jürgen, Schick, Fritz, Machicao, Fausto, Stefan, Norbert, Claussen, Claus D., Häring, Hans-Ulrich, Fritsche, Andreas, Staiger, Harald
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2010
Sujets:
Genetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828665/
https://ncbi.nlm.nih.gov/pubmed/20028944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1050
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