Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered to Alveolar Bone Defects Exhibits Safety and Biodistribution Profiles Favorable for Clinical Use

Platelet-derived growth factor (PDGF) gene therapy offers promise for tissue engineering of tooth-supporting alveolar bone defects. To date, limited information exists regarding the safety profile and systemic biodistribution of PDGF gene therapy vectors when delivered locally to periodontal osseous...

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Hlavní autoři: Chang, Po-Chun, Cirelli, Joni A., Jin, Qiming, Seol, Yang-Jo, Sugai, James V., D'Silva, Nisha J., Danciu, Theodora E., Chandler, Lois A., Sosnowski, Barbara A., Giannobile, William V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2009
Témata:
Scientific Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828639/
https://ncbi.nlm.nih.gov/pubmed/19199824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.114
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