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In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy.

To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked phospholipid or one of several ester-linked phosph...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Derksen, J T, Baldeschwieler, J D, Scherphof, G L
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3200855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9768
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